1-Ethylpiperazine → HCID 10970041, compound

HRID 49756Notes

Reaction equation

HRID 49756 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11][C:10]3=[CH:12][CH:13]=[CH:14][N:9]3[CH2:8][C:7](=O)[C:6]=2[CH:16]=1.[CH2:17]([N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)[CH3:18]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11][C:10]3=[CH:12][CH:13]=[CH:14][N:9]3[CH:8]=[C:7]([N:22]3[CH2:23][CH2:24][N:19]([CH2:17][CH3:18])[CH2:20][CH2:21]3)[C:6]=2[CH:16]=1

Participants

3

Reactant 2

HCID 791961-EthylpiperazineHCID 10490872HCID 10490872, compound

Product 1

HCID 10970041HCID 10970041, compound

Procedure

Starting from 7-chloro-9,10-dihydropyrrolo[2,1-b][1,3]benzothiazepin-9-one (0.19 g, 0.76 mmol) and N-ethylpiperazine (0.70 mL, 6.13 mmol), the title compound was obtained following the above described procedure for (1). After purification, 0.19 g of the desired product were obtained as a white solid (yield 74%).

Sources & evidence

ORD record
ord-8b36773a880f40459c48d159426a9457
Source dataset
uspto-grants-2004_03
Patent number
US06710041B2

Reaction notes

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