Hydrochloric Acid → HCID 22319741, compound

Participants

Reaction Steps

1.7 g of NaOH pellets are added to 8.1 g of methyl 3-(4-allylbenzoyl)-2-butylbenzofuran-5-carboxylate in 40 ml of methanol, 200 ml of dioxane and 40 ml of water. The mixture is stirred at ambient temperature for 24 hours. It is neutralized to pH 7 with concentrated hydrochloric acid and then evaporated. Water is added and the acid is regenerated with concentrated hydrochloric acid. Extraction is carried out three times with ether and the extracts are washed with water and then with an aqueous NaCl solution. They are dried over Na2SO4 and then concentrated.

Provenance & Evidence