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HRID49765

反应详情

EQUATION

反应方程式

HRID 49765 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)O
HCID2724762

tert-Butoxycarbonyl-L-isoleucine

C11H21NO4

结构：Cl.FC1(F)CNC1
HCID2758247

3,3-Difluoroazetidine hydrochloride

C3H6ClF2N

PRODUCTS

生成物

1
结构：CCC(C)[C@H](N)C(=O)N1CC(F)(F)C1.Cl
HCID69713143

未命名化合物

PROCEDURE

实验过程

(S)-2-amino-1-(3,3-difluoro-azetidin-1-yl)-3-methyl-pentan-1-one hydrochloride was prepared by coupling 3,3-difluoro-azetidine hydrochloride (WO 0047582) with Boc-(L)-isoleucine followed by HCl deprotection as analogously described in Example 1 (mp 195° C. dec.).