反应详情

温度

100 °C

The title compound was prepared according to the procedure described in U.S. Pat. No. 4,260,767 (1981). A mixture of 2-bromo-3-methylpyridine (29.0 g, 169 mmol) and hydrazine monohydrate (60 mL, 1.24 mol) was heated and stirred at 100° C. for 4 hours. The mixture was ice cooled, and the resulting crude crystals were filtered. The crystals were washed with cold water and air dried, and recrystallized from chloroform/hexane to give the title compound (12.5 g, 60% yield).

1. customThe title compound was prepared
2. temperaturewas heated
3. temperaturecooled
4. filtrationthe resulting crude crystals were filtered
5. washThe crystals were washed with cold water and air
6. customdried
7. customrecrystallized from chloroform/hexane