1-Iodopropane → HCID 22320270, compound

HRID 498037Notes

Reaction equation

[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[F:12])[NH:8][C:7]1[N:13]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=3)[N:14]=[C:15]([CH3:16])[C:6]=1[C:5]2=[O:23].I[CH2:25][CH2:26][CH3:27]>>[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[F:12])[N:8]=[C:7]1[N:13]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=3)[N:14]=[C:15]([CH3:16])[C:6]1=[C:5]2[O:23][CH2:25][CH2:26][CH3:27]

Participants

Reactant 2

HCID 336431-Iodopropane

HCID 135482311HCID 135482311, compound

Product 1

HCID 22320270HCID 22320270, compoundYield 27%

Procedure

Following the procedure described in Example 2-16, from 6,7-difluoro-3-methyl-1-(2-pyridinyl)-1,9-dihydro-4H-pyrazolo[3,4-b]quinolin-4-one and 1-iodopropane was prepared the title compound (27% yield).

Sources & evidence

ORD record: ord-c2ddb861384e4cb6833eacdba422c417
Source dataset: uspto-grants-2005_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06949648B2

Reaction notes

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