反应详情

A solution of aminocrotononitrile (8.21 g, 100 mmol) and 3-hydrazinopyridine dihydrochloride (20.7 g, 114 mmol) in water (50 mL) was mixed with conc. hydrochloric acid (15 mL), and the mixture was heated under reflux for 30 minutes. The solution was allowed to cool to room temperature, and the reaction solvent was evaporated under reduced pressure, and the resulting crystals were collected by filtration. The crystals obtained were washed with water and air dried to give the title compound (13.6 g, 55% yield).

1. temperaturethe mixture was heated
2. temperatureunder reflux for 30 minutes
3. customthe reaction solvent was evaporated under reduced pressure
4. filtrationthe resulting crystals were collected by filtration
5. customThe crystals obtained
6. washwere washed with water and air
7. customdried