HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-(4-Methoxyphenyl)-4-(2-phenylethoxy)-1-butanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethylether heptane | HCID 21897273 | — |
| Reactant | 2-(4-Methoxyphenyl)-2-[3-(2-phenylethoxy)propyl]-1,3-dioxolane | HCID 22320892 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-(4-Methoxyphenyl)-4-(2-phenylethoxy)-1-butanone | HCID 22320898 | 78% |
Reaction Steps
This compound was synthesized as described under 5.c) with 0.8 ml of HCl (1N) and 0.65 g (1.9 mmol) of 2-(4-methoxyphenyl)-2-[3-(2-phenylethoxy)propyl]-1,3-dioxolane obtained under a) in 50 ml of THF. Column chromatography (SiO2, heptane/ether 4:1) gave 0.44 g (78%) of white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949680B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-dabe647cdaeb467188cb6f212d05ffa7 |
| Source note | uspto-grants-2005_09 |