HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chloro-5-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester → tert-Butyl (2-amino-4-chloro-5-fluorophenyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chloro-5-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester | HCID 69486584 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Product | tert-Butyl (2-amino-4-chloro-5-fluorophenyl)carbamate | HCID 67375046 | — |
Reaction Steps
The title compound was prepared from (4-chloro-5-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example A6) (16.48 g, 56.7 mmol) by hydrogenation with 5% Pt/C according to the general procedure J (method a). Obtained as a brown solid (14.78 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-7a092a66c7cf4cacac512288c4178497 |
| Source note | uspto-grants-2005_09 |