HCID 86586793, compound → Carbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester

HRID 498193Notes

Reaction equation

HRID 498193 reaction equation
[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][C:16]([F:19])([F:18])[F:17])[C:11]([C:20]([F:23])([F:22])[F:21])=[CH:10][C:9]=1[N+:24]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pt]>[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][C:16]([F:17])([F:19])[F:18])[C:11]([C:20]([F:22])([F:23])[F:21])=[CH:10][C:9]=1[NH2:24])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 86586793HCID 86586793, compound

Product 1

HCID 76849205Carbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester

Reagents, catalysts & solvents 1

HCID 23939PlatinumCatalyst

Procedure

The title compound was prepared from [2-nitro-5-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example A) by hydrogenation with 5% Pt/C according to the general procedure J (method a). Obtained as a yellow solid (17.374 g).

Sources & evidence

ORD record
ord-7064c7275e334b4393897ca09fa3ab72
Source dataset
uspto-grants-2005_09
Patent number
US06949542B2

Reaction notes

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