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HRID4982

反应详情

EQUATION

反应方程式

HRID 4982 的结构方程式

REACTANTS

反应物

1
结构：CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1
HCID58901353

未命名化合物

PRODUCTS

生成物

2
结构：CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)OCc1ccccc1
HCID16742166

未命名化合物

结构：CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1
HCID58901353

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O=C(O)C(F)(F)F
溶剂HCID6422

未命名化合物

PROCEDURE

实验过程

Boc-Leu-Ala-OBzl was prepared by the procedure for dipeptide synthesis in Example 2. Boc-Leu-Ala-OBzl (23.7 g, 57.7 mmoles) was dissolved in 40 mL of anhydrous trifluoroacetic acid. After 15 min, excess trifluoroacetic acid was removed by evaporation and the residue was treated with ether to yield H-Leu-Ala-OBzl.trifluoroacetic acid as a crystalline product (22.8 g).

WORKUP

后处理

  1. customexcess trifluoroacetic acid was removed by evaporation
  2. additionthe residue was treated with ether