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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498289Generated: October 30, 2026

tert-Butyl (3-amino-2'-fluoro-[1,1'-biphenyl]-4-yl)carbamate → HCID 86589254, compound

https://huagongshe.com/reaction/498289

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl (3-amino-2'-fluoro-[1,1'-biphenyl]-4-yl)carbamateHCID 67361423—
ReactantHCID 69486831HCID 69486831—
ProductHCID 86589254HCID 86589254—

Reaction Steps

The title compound was prepared from (3-amino-2′-fluoro-biphenyl-4-yl)-carbamic acid tert-butyl ester [CAS-No. 335255-65-7] (227 mg, 0.75 mmol) and 3-[3-(6-methoxy-pyridazin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K7) (246 mg, 0.75 mmol) according to the general procedure M. Obtained as an off-white amorphous substance (352 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-e12602c7a2604b058375d1f0d0698b63
Source noteuspto-grants-2005_09