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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498364Generated: October 30, 2026

3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester → {5-Ethoxy-2-[3-oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/498364

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl esterHCID 11266473—
ReactantHCID 69486521HCID 69486521—
Product{5-Ethoxy-2-[3-oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl esterHCID 86589329—

Reaction Steps

The title compound was prepared from (2-amino-5-ethoxy-phenyl)-carbamic acid tert-butyl ester (Example J14) (194 mg, 0.77 mmol) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K1) (224 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow foam (203 mg, 55%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-a3235c28375c405cb6f451caadd31006
Source noteuspto-grants-2005_09