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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498415Generated: November 3, 2026

3-[3-(6-Cyclopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester → HCID 86589380, compound

https://huagongshe.com/reaction/498415

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(6-Cyclopropyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489384—
ReactantHCID 69489890HCID 69489890—
ProductHCID 86589380HCID 86589380—

Reaction Steps

The title compound was prepared from (2-amino-5-propoxy-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J35) (251 mg, 0.75 mmol) and 3-[3-(6-cyclo-propyl-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K21) (253 mg, 0.75 mmol) according to the general procedure M. Obtained as a yellow foam (372 mg, 83%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-5398b269ff9148168806827ed26f5123
Source noteuspto-grants-2005_09