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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498418Generated: November 2, 2026

3-[3-(2,6-Dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester → HCID 86589383, compound

https://huagongshe.com/reaction/498418

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(2,6-Dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489240—
ReactantHCID 69489890HCID 69489890—
ProductHCID 86589383HCID 86589383—

Reaction Steps

The title compound was prepared from (2-amino-5-propoxy-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J35) (251 mg, 0.75 mmol) and 3-[3-(2,6-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K15) (244 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow solid (172 mg, 49%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-02a985de74054f02a7a01c36ba5c8932
Source noteuspto-grants-2005_09