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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498473Generated: October 31, 2026

HCID 69486907, compound → HCID 86589438, compound

https://huagongshe.com/reaction/498473

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486907HCID 69486907—
Reactanttert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamateHCID 69486983—
ProductHCID 86589438HCID 86589438—

Reaction Steps

The title compound was prepared from (2-amino-4-chloro-5-methyl-phenyl)-carbamic acid tert-butyl ester (Example J22) (257 mg, 1.0 mmol) and (RS)-3-oxo-3-{3-[2-(tetrahydro-pyran-2-yloxymethyl)-pyridin-4-yl]-phenyl}-propionic acid tert-butyl ester (Example K40) (412 mg, 1.0 mmol) according to the general procedure M. Obtained as a light brown solid (510 mg, 86%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-03c7902696114bdda7766f09fe7fe815
Source noteuspto-grants-2005_09