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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498526Generated: October 30, 2026

Trifluoroacetic acid → HCID 22317600, compound

https://huagongshe.com/reaction/498526

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86589471HCID 86589471—
SolventDichloromethaneHCID 6344—
ProductHCID 22317600HCID 22317600—

Reaction Steps

The title compound was prepared from {2′-fluoro-3-[3-oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert-butyl ester (Example M26) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light brown solid (127 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-27674feb927146b4a2b07fdce634c99e
Source noteuspto-grants-2005_09