O-Phenylenediamine → HCID 22317257, compound

HRID 498531Notes

Reaction equation

HRID 498531 reaction equation
[C:1]1([NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH2:7].C([O:13][C:14](=O)[CH2:15][C:16](=O)[C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([C:23]2[CH:24]=[N:25][CH:26]=[CH:27][CH:28]=2)[CH:18]=1)(C)(C)C>C1(C)C(C)=CC=CC=1>[N:25]1[CH:26]=[CH:27][CH:28]=[C:23]([C:19]2[CH:18]=[C:17]([C:16]3[CH2:15][C:14](=[O:13])[NH:8][C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=4[N:7]=3)[CH:22]=[CH:21][CH:20]=2)[CH:24]=1

Participants

4

Reactant 2

HCID 7243O-PhenylenediamineHCID 112664733-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester

Product 1

HCID 22317257HCID 22317257, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

The title compound was prepared from 1,2-phenylenediamine (81 mg, 0.75 mmol) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K1) (223 mg, 0.75 mmol) by refluxing in xylene according to the general procedure M. Obtained as a white solid (204 mg).

Sources & evidence

ORD record
ord-54571bad6cb545278efa37af5d38a3bb
Source dataset
uspto-grants-2005_09
Patent number
US06949542B2

Reaction notes

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