HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Phenylenediamine → HCID 22317983, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Phenylenediamine | HCID 7243 | — |
| Reactant | 3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester | HCID 69489307 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 22317983 | HCID 22317983 | — |
Reaction Steps
The title compound was prepared from commercially available 1,2-phenylendiamine (108 mg, 1.0 mmol) and 3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K12) (311 mg, 1.0 mmol) in xylene (20 ml) under reflux conditions for 2 h according to the general procedure M. Obtained as an off-white solid (230 mg, 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-6f7132fb004040b19e6676b3b51688ab |
| Source note | uspto-grants-2005_09 |