HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 22317833, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86589363 | HCID 86589363 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22317833 | HCID 22317833 | — |
Reaction Steps
The title compound was prepared from [2-[3-oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-4-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester (Example M179) (266 mg, 0.5 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as an off-white solid (175 mg, 85%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-b3e7ab15fc534cbfb2fb691058f408e8 |
| Source note | uspto-grants-2005_09 |