HCID 59420839, compound → 7-Mercapto-2-(2,2,2-trifluoroethyl)-1(2H)-isoquinolinone

Participants

Reaction Steps

2-(2,2,2-trifluoroethyl)-7-((triisopropylsilyl)sulfanyl)isoquinolin-1(2H)-one was dissolved in a solution of hydrochloric acid in methanol (2 ml) and tetrahydrofuran (2 ml) and stirred at room temperature for 2 hours or until disappearance of starting material. Reaction mixture was concentrated to give the desired material (quant yield).

Provenance & Evidence