Piperazine → HCID 67523240, compound

Participants

Reaction Steps

To a solution of 6′-chloro-[2,3′]bipyridinyl (0.275 g, 1.440 mmol) in acetonitrile (10 mL) was added piperazine (0.310 g, 3.600 mmol) and the mixture was stirred at reflux for 32 hours. The solvent was removed in vacuo. The residue was dissolved in dichloromethane and washed with saturated NaHCO3 solution (10 mL). Organic layer was separated, dried over MgSO4 and filtered. The filtrate was use in the next step without isolation of the product.

Provenance & Evidence