HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-[(1-methylpiperidin-2-yl)methyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68457042 | HCID 68457042 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 1-[(1-methylpiperidin-2-yl)methyl]piperazine | HCID 4914648 | 133.3% |
Reaction Steps
1 ml of a 4M solution of HCl in dioxane is added to a solution of 3.28 g of the compound obtained in step 6.3, in 1 ml of dioxane. The medium is stirred at AT for 48 h. The medium is filtered, and the solid is rinsed with ether and then dried, to give 2.9 g of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07767681B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-038887936d82412693aec058f47b4d05 |
| Source note | uspto-grants-2010_08 |