反应详情

A mixture of 3-methyl-2-mercaptobenzoic acid (2.40 g, 14.3 mmol), 2-cyanopyridine (1.20 g, 11.9 mmol) and pyridine (50.0 ml) was refluxed for 9 hrs as described in Example 9. After cooling, the precipitated crystals were collected by filtration and recrystallized from hexane-tetrahydrofuran to give the titled compound (1.60 g, 52%)

1. temperaturewas refluxed for 9 hrs
2. temperatureAfter cooling
3. filtrationthe precipitated crystals were collected by filtration
4. customrecrystallized from hexane-tetrahydrofuran