Hydrochloric Acid → 2-Aminoquinoline-6-carboxylic Acid Hydrochloride

HRID 49928Notes

Reaction equation

HRID 49928 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:12]([O:14]CC)=[O:13])[CH:8]=2)[N:3]=1.[ClH:17]>>[ClH:17].[NH2:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:12]([OH:14])=[O:13])[CH:8]=2)[N:3]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 17834348Ethyl 2-aminoquinoline-6-carboxylate

Product 1

HCID 691425542-Aminoquinoline-6-carboxylic Acid Hydrochloride

Procedure

330 mg of ethyl 2-aminoquinoline-6-carboxylate was stirred in 30 ml of 6 M hydrochloric acid at 80° C. overnight. The solvent was evaporated, and the residue was washed with ethyl acetate to obtain the title compound.

Workup

  1. customThe solvent was evaporated
  2. washthe residue was washed with ethyl acetate

Sources & evidence

ORD record
ord-433f363192db47b18bcac0f46394763f
Source dataset
uspto-grants-2004_03
Patent number
US06710056B2

Reaction notes

Loading…