Potassium Carbonate → HCID 22939400, compound

HRID 499286Notes

Reaction equation

HRID 499286 reaction equation
C([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]2[S:13][C:14]3[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=3[C:16](=[O:18])[N:17]=2)[N:7]=1)(=O)C.C(=O)([O-])[O-].[K+].[K+]>CO>[OH:4][CH2:5][C:6]1[N:7]=[C:8]([C:12]2[S:13][C:14]3[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=3[C:16](=[O:18])[N:17]=2)[CH:9]=[CH:10][CH:11]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 59750183HCID 59750183, compound

Product 1

HCID 22939400HCID 22939400, compoundYield 70.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of [6-(4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]methyl acetate (0.30 g, 1.00 mmol), potassium carbonate (0.004 g, 0.03 mmol) and methanol (30 ml) was stirred under nitrogen atmosphere at room temperature for 2 hrs. The reaction mixture was concentrated, dissolved in hot ethanol (10 ml) and filtered. The filtrate was concentrated under reduced pressure and the residue was recrystallized from ethanol to give the titled compound (0.19 g, 70%).

Workup

  1. concentrationThe reaction mixture was concentrated
  2. dissolutiondissolved in hot ethanol (10 ml)
  3. filtrationfiltered
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. customthe residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-fdccca8cd61b4381925d13ff843b9e5f
Source dataset
uspto-grants-2010_08
Patent number
US07767665B2

Reaction notes

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