Triethylamine → 2-[6-(Pentylthio)-2-pyridyl]-4H-1,3-benzothiazine-4-one

Beteiligte Stoffe

Reaktionsschritte

A mixture of methyl thiosalicylate (1.21 g, 7.2 mmol), 2-cyano-6-pentylthiopyridine (1.48 g, 7.2 mmol), triethylamine (1.5 ml, 10.8 mmol) and toluene (30 ml) was refluxed for 48 hrs. The reaction mixture was concentrated under reduced pressure to give the precipitated crystals, which were recrystallized from ethyl acetate-hexane to give the titled compound (1.09 g, 44%).

Herkunft & Nachweise