反应详情

A mixture of methyl thiosalicylate (1.21 g, 7.2 mmol), 2-cyano-6-pentylthiopyridine (1.48 g, 7.2 mmol), triethylamine (1.5 ml, 10.8 mmol) and toluene (30 ml) was refluxed for 48 hrs. The reaction mixture was concentrated under reduced pressure to give the precipitated crystals, which were recrystallized from ethyl acetate-hexane to give the titled compound (1.09 g, 44%).

1. temperaturewas refluxed for 48 hrs
2. concentrationThe reaction mixture was concentrated under reduced pressure
3. customto give the precipitated crystals, which
4. customwere recrystallized from ethyl acetate-hexane