反应详情

A mixture of methyl thiosalicylate (0.85 g, 5.1 mmol), 2-cyano-6-methylpyridine (0.60 g, 5.1 mmol), triethylamine (1.10 ml, 7.9 mmol) and toluene (1.1 ml) was refluxed for 9 hrs. After cooling, the precipitated crystals were collected by filtration and recrystallized from ethanol to give the titled compound (0.71 g, 55%).

1. temperaturewas refluxed for 9 hrs
2. temperatureAfter cooling
3. filtrationthe precipitated crystals were collected by filtration
4. customrecrystallized from ethanol