m-Chloroperbenzoic acid → HCID 59750294, compound

HRID 499406Notes

Reaction equation

HRID 499406 reaction equation
[C:1]([S:5][C:6]1[N:11]=[C:10]([C:12]2[S:13][C:14]3[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=3[C:16](=[O:18])[N:17]=2)[CH:9]=[CH:8][CH:7]=1)([CH3:4])([CH3:3])[CH3:2].ClC1C=CC=C(C(OO)=[O:31])C=1>C(Cl)(Cl)Cl>[C:1]([S:5]([C:6]1[N:11]=[C:10]([C:12]2[S:13][C:14]3[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=3[C:16](=[O:18])[N:17]=2)[CH:9]=[CH:8][CH:7]=1)=[O:31])([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 59750457HCID 59750457, compound

Product 1

HCID 59750294HCID 59750294, compoundYield 75.7%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

2-[6-(tert-Butylthio)-2-pyridyl]-4H-1,3-benzothiazine-4-one (0.15 g, 0.46 mmol) was dissolved in chloroform (30 ml), and a solution of 3-chloroperbenzoic acid (ca. 77%, 0.10 g, 0.46 mmol) in chloroform (10 ml) was added dropwise thereto. The reaction mixture was stirred at room temperature for 1 hr. The solvent was evaporated, and the residue was recrystallized from ethanol to give the titled compound (0.12 g, 75%) as white crystals.

Workup

  1. customThe solvent was evaporated
  2. customthe residue was recrystallized from ethanol

Sources & evidence

ORD record
ord-4e169f2355904d27910e33b57e3a690f
Source dataset
uspto-grants-2010_08
Patent number
US07767665B2

Reaction notes

Loading…