Hydrochloric Acid → HCID 178493226, compound

HRID 49945Notes

Reaction equation

FC(F)(F)C(O)=O.[NH:8]([C:12]1[CH:21]=[CH:20][C:15]([C:16]([O:18]C)=[O:17])=[C:14]([O:22][CH3:23])[CH:13]=1)[C:9]([NH2:11])=[NH:10].[ClH:24]>>[ClH:24].[NH:8]([C:12]1[CH:21]=[CH:20][C:15]([C:16]([OH:18])=[O:17])=[C:14]([O:22][CH3:23])[CH:13]=1)[C:9]([NH2:11])=[NH:10]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 178498156HCID 178498156, compound

Product 1

HCID 178493226HCID 178493226, compound

Conditions

Temperature: 80 °C

Procedure

384 mg of methyl 4-guanidino-2-methoxybenzoate trifluoroacetate was dissolved in 8 ml of 3 M hydrochloric acid, and they were stirred at 80° C. for 2.5 hours. The solvent was evaporated to obtain the title compound.

Workup

customThe solvent was evaporated

Sources & evidence

ORD record: ord-f03d6521fe21468caf92eef68013cb3c
Source dataset: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06710056B2

Reaction notes

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