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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49949Generated: October 28, 2026

Hydrochloric Acid → 4-Methoxybiphenyl-3-carboxylic acid

https://huagongshe.com/reaction/49949

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethyl 2-Methoxy-5-phenylbenzoateHCID 17834364—
Solvent1,4-Dioxane--water (1/1)HCID 21886435—
Product4-Methoxybiphenyl-3-carboxylic acidHCID 17834343—

Reaction Steps

0.84 g (3.33 mmol) of methyl 2-Methoxy-5-phenylbenzoate was stirred under heating at 80° C. in a solvent mixture of dioxane/water containing 4 M of hydrogen chloride for 7 hours. The solvent was evaporated to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06710056B2
Source datasetuspto-grants-2004_03
ORD IDord-3a78d3bcc9ab4f0c9ba39807ab390c2c
Source noteuspto-grants-2004_03