HCID 22939353, compound → HCID 59750359, compound

HRID 499629Notes

Reaction equation

HRID 499629 reaction equation
C([O:8][C:9]1[N:14]=[C:13]([C:15]2[S:16][C:17]3[CH:25]=[CH:24][CH:23]=[CH:22][C:18]=3[C:19](=[O:21])[N:20]=2)[CH:12]=[CH:11][CH:10]=1)C1C=CC=CC=1>FC(F)(F)C(O)=O>[O:8]=[C:9]1[NH:14][C:13]([C:15]2[S:16][C:17]3[CH:25]=[CH:24][CH:23]=[CH:22][C:18]=3[C:19](=[O:21])[N:20]=2)=[CH:12][CH:11]=[CH:10]1

Participants

3

Reactant 1

HCID 22939353HCID 22939353, compound

Product 1

HCID 59750359HCID 59750359, compoundYield 69%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

2-(6-(Benzyloxy)-2-pyridyl)-4H-1,3-benzothiazine-4-one (0.15 g, 0.43 mmol) was dissolved in trifluoroacetic acid (10 ml), and the mixture was stirred at room temperature for 15 hrs. The solvent was evaporated, and the residue was recrystallized from chloroform-hexane to give the titled compound (0.07 g, 69%).

Workup

  1. customThe solvent was evaporated
  2. customthe residue was recrystallized from chloroform-hexane

Sources & evidence

ORD record
ord-21742255427b4962affbdcf27c0acfa8
Source dataset
uspto-grants-2010_08
Patent number
US07767665B2

Reaction notes

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