HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzyl bromide → HCID 16041750, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Reactant | 1-Azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol | HCID 42625856 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 16041750 | HCID 16041750 | 101.9% |
Reaction Steps
Following the general procedure outlined in Example 2, 1-azabicyclo[2.2.1]hept-4-yl(diphenyl)methanol (33.2 mg, 0.119 mmol) and 1-(bromomethyl)-4-nitrobenzene (45.9 mg, 0.176 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) were reacted to give the desired product (32.7 mg, 51%). EI-MS m/z 459 (M+) Rt (1.83 min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07767691B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-57e07639c1584aeba61feaaf5d1ea75f |
| Source note | uspto-grants-2010_08 |