Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | ethyl 1H-imidazole-2-carboxylate | HCID 549404 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | HCID 178470305 | HCID 178470305 | — |
Reaction Steps
16.08 g (114.7 mmol) of ethyl imidazole-2-carboxylate are dissolved in 71.7 ml of concentrated sulphuric acid while cooling in ice. Then 71.7 ml of 100% strength fuming nitric acid are added dropwise. The reaction solution is stirred at 50 to 60° C. for 3 h and, after cooling, poured into 800 ml of ice/water mixture. The crystals which separate out are filtered off with suction and washed with 1500 ml of ice-water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07767704B2 |
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| Source dataset | uspto-grants-2010_08 |
|---|
| ORD ID | ord-e3f212eb2cb5456a91c663e004cdc4d2 |
|---|
| Source note | uspto-grants-2010_08 |
|---|
