反应详情

A solution of 2-(1-piperazinyl)-1-ethanol (6.5 g 0.05 mol) in DCM (5 mL) was treated with acetic acid anhydride (5.1 g, 0.05 mol), added dropwise. During addition, the reaction temperature rose from 22 to 60° C. The reaction mixture was evaporated several times with toluene to yield 5.6 g (65%) of the sub-title compound.

1. additionadded dropwise
2. additionDuring addition
3. customrose from 22 to 60° C
4. customThe reaction mixture was evaporated several times with toluene