反应详情

温度

78 °C

The title compound from example 30.1 (4 g, 24 mmol) was dissolved in ethanol and stirred at 78° C. Hydrazine hydrate (5.8 mL, 120 mmol) was added via a syringe and the reaction was stirred for 3 h at 78° C., at which time the starting material was no longer visible by TLC. The reaction mixture (clear solution) was then cooled to room temperature, and diluted with diethyl ether to precipitate the product which was collected by vacuum filtration to yield the title compound as a pale yellow solid (3.13 g, 78%).

1. stirringthe reaction was stirred for 3 h at 78° C., at which time the starting material
2. temperatureThe reaction mixture (clear solution) was then cooled to room temperature
3. customto precipitate the product which
4. filtrationwas collected by vacuum filtration