Triethylamine → HCID 86602198, compound

HRID 500582Notes

Reaction equation

HRID 500582 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[S:9](Cl)(=[O:11])=[O:10].[NH2:13][C:14]1[C:19]([OH:20])=[CH:18][CH:17]=[CH:16][C:15]=1[CH3:21].C(N(CC)CC)C>C(Cl)Cl>[NH2:13][C:14]1[C:15]([CH3:21])=[CH:16][CH:17]=[CH:18][C:19]=1[O:20][S:9]([C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])(=[O:11])=[O:10]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 204419Benzenesulfonyl chloride, 2,4-dichloro-HCID 30141382-Amino-m-cresol

Product 1

HCID 86602198HCID 86602198, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a mixture of 2,4-dichlorobenzenesulfonyl chloride (20.2 g, 82.3 mmol) and 2-amino-m-cresol (11 g, 89.4 mmol) in 200 mL of methylene chloride, triethylamine (8.5 g, 83.4 mmol) was added dropwise at 5° C. The mixture was stirred at ambient temperature for 16 hours.

Workup

  1. additionwas added dropwise at 5° C

Sources & evidence

ORD record
ord-28d7b2bd3d6842509216c3bd7d2b18c6
Source dataset
uspto-grants-2010_08
Patent number
US07772237B2

Reaction notes

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