4-Nitrophenol → 2-Bromo-7-(4-nitrophenoxy)thieno[3,2-b]pyridine

Participants

Role	Name	HCID	Charge
Reactant	4-Nitrophenol	HCID 980	—
Reactant	2-Bromo-7-chlorothieno[3,2-b]pyridine	HCID 18382774	—
Reactant	2-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine	HCID 59424521	—
Product	2-Bromo-7-(4-nitrophenoxy)thieno[3,2-b]pyridine	HCID 59424461	48%

Reaction Steps

Starting from the compound 41 (scheme 8) and following the procedure described above for the synthesis of compound 42 (scheme 8) but replacing 2-fluoro-4-nitrophenol for 4-nitrophenol, title compound 197 was obtained in 48% yield. LRMS (M+1) 350.9 (100%). 352.9 (100%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07772247B2
Source dataset	uspto-grants-2010_08
ORD ID	ord-9bd379743d434f18995c1b6c49f7fd14
Source note	uspto-grants-2010_08