HRID500848

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2735821

4-Chlorothieno[3,2-d]pyrimidine

C6H3ClN2S

HCID2808547

thieno[2,3-d]pyrimidin-4(3H)-one

C6H4N2OS

PRODUCTS

生成物

HCID736618

4-Chlorothieno[2,3-d]pyrimidine

C6H3ClN2S

收率 93%

PROCEDURE

实验过程

Starting from thieno[2,3-d]pyrimidin-4(3H)-one (204) [J. Med. Chem., 1999, 42, 26, 5437-5447, Bull. Soc. Chim. Fr., 1975, 587-591] and following the procedure described above for the synthesis of compound 20 (scheme 4, example 22), title compound 205 was obtained in 93% yield. LRMS (M+1) 169.1 (100%), 171.1 (32%).