HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorothieno[3,2-d]pyrimidine → 4-Chlorothieno[2,3-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorothieno[3,2-d]pyrimidine | HCID 2735821 | — |
| Reactant | thieno(2,3-d)pyrimidin-4(3H)-one | HCID 2808547 | — |
| Product | 4-Chlorothieno[2,3-d]pyrimidine | HCID 736618 | 93% |
Reaction Steps
Starting from thieno[2,3-d]pyrimidin-4(3H)-one (204) [J. Med. Chem., 1999, 42, 26, 5437-5447, Bull. Soc. Chim. Fr., 1975, 587-591] and following the procedure described above for the synthesis of compound 20 (scheme 4, example 22), title compound 205 was obtained in 93% yield. LRMS (M+1) 169.1 (100%), 171.1 (32%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772247B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-ce5cd134ddeb415897b312bb36ccb222 |
| Source note | uspto-grants-2010_08 |