4-Nitrophenol → 7-(4-Nitrophenoxy)thieno[3,2-b]pyridine

Participants

Role	Name	HCID	Charge
Reactant	4-Nitrophenol	HCID 980	—
Reactant	7-Chlorothieno[3,2-b]pyridine	HCID 11275251	—
Reactant	7-(2-fluoro-4-nitrophenoxy)-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamide	HCID 59424475	—
Product	7-(4-Nitrophenoxy)thieno[3,2-b]pyridine	HCID 59424636	89%

Reaction Steps

Staring from the chloride 2, following the procedure described above for the synthesis of compound 6 (scheme 1, example 1) but substituting 2-fluoro-4-nitrophenol for 4-nitrophenol, title compound 212 was obtained in 89% yield. MS (m/z) 273.0 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07772247B2
Source dataset	uspto-grants-2010_08
ORD ID	ord-68f7267ff4c44d788ce45c20af999671
Source note	uspto-grants-2010_08