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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 500888Generated: October 26, 2026

Pyrazole → N-(4-(2-(1H-Pyrazol-1-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide

https://huagongshe.com/reaction/500888

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrazoleHCID 1048—
Reactant4-MethylpyrazoleHCID 3406—
ReactantN-(4-(2-(4-Methyl-1H-pyrazol-1-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamideHCID 86604190—
ProductN-(4-(2-(1H-Pyrazol-1-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamideHCID 86604191—

Reaction Steps

Following the procedures described above for the synthesis of compound 258a (example 215, scheme 58) but replacing 4-methyl-1H-pyrazole in the step 1 with 1H-pyrazole, title compound 258b was obtained. Characterization of 258b is provided in the table 23.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772247B2
Source datasetuspto-grants-2010_08
ORD IDord-49e7b332fefd4893821c1fc34710d667
Source noteuspto-grants-2010_08