HRID500921

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cn1ccnc1-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3)c2s1

HCID11962454

未命名化合物

HCID22143563

7-Chloro-2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridine

C11H8ClN3S

结构：Cl.Cl.Cn1ccnc1-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4F)cc3F)c2s1

HCID86604196

未命名化合物

PRODUCTS

生成物

HCID59424528

未命名化合物

收率 31%

PROCEDURE

实验过程

Starting from the compound 214 (scheme 46) and following the procedures described above for the synthesis of compound 228 (example 202) and 303a (example 232), title compound 234 was obtained in 31% yield as an off-white solid. H NMR (d-DMSO) δ (ppm): 12.34(s, 1H), 11.81(s, 1H), 8.68(m, 1H,), 8.24(s, 1H), 7.79(m, 3H), 7.62(s, 1H), 7.40-7.13(m, 6H), 6.86(d, 1H), 4.02(s, 3H), 3.93(s, 2H). MS (m/z): 518.1(M+H) (found).