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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 501236Generated: October 27, 2026

Acetic Anhydride → N-(2,3-Dihydro-1H-inden-2-yl)acetamide

https://huagongshe.com/reaction/501236

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
ReactantEthyl AcetateHCID 8857—
Reactant2-Aminoindan hydrochlorideHCID 122764—
SolventTriethylamineHCID 8471—
ProductN-(2,3-Dihydro-1H-inden-2-yl)acetamideHCID 12452137—

Reaction Steps

Acetic anhydride (3.55 ml) was dropped to the mixture of 6.37 g 2-amino indane hydrochloride, 60 ml of ethyl acetate and 10.4 ml triethylamine and the reaction mixture was stirred at room temperature for 15 hours. The solvents were evaporated in vacuo and the solid residue was digested with water, filtered and dried at 40° C. in vacuo.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772257B2
Source datasetuspto-grants-2010_08
ORD IDord-c7d4fc384e50469a9368bf8d6b2505af
Source noteuspto-grants-2010_08