Hydrochloric Acid → HCID 178428006, compound

HRID 501246Notes

Reaction equation

HRID 501246 reaction equation
[CH3:1][C:2]1([CH3:26])[CH2:6][CH2:5][S:4](=[O:8])(=[O:7])[N:3]1[C:9]1[C:20]([S:21]([CH3:24])(=[O:23])=[O:22])=[CH:19][C:12]([C:13]([NH:15][C:16]([NH2:18])=[NH:17])=[O:14])=[C:11]([CH3:25])[CH:10]=1.[ClH:27]>CC(C)=O>[ClH:27].[CH3:1][C:2]1([CH3:26])[CH2:6][CH2:5][S:4](=[O:7])(=[O:8])[N:3]1[C:9]1[C:20]([S:21]([CH3:24])(=[O:23])=[O:22])=[CH:19][C:12]([C:13]([NH:15][C:16]([NH2:18])=[NH:17])=[O:14])=[C:11]([CH3:25])[CH:10]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 178428005HCID 178428005, compound

Product 1

HCID 178428006HCID 178428006, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

22.5 mg of N-[4-(3,3-dimethyl-1,1-dioxoisothiazolidin-2-yl)-5-methanesulfonyl-2-methylbenzoyl]guanidine were taken up in 5 ml of acetone, and 0.5 ml of a 4N aqueous HCl solution was added. The volatile constituents were removed in vacuo and then coevaporated 3 times with 5 ml of toluene each time. 23.9 mg of an amorphous solid were obtained.

Workup

  1. customThe volatile constituents were removed in vacuo

Sources & evidence

ORD record
ord-39d845c26d064a678973709b598d080d
Source dataset
uspto-grants-2010_08
Patent number
US07772262B2

Reaction notes

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