Hydrochloric Acid → HCID 178427992, compound

HRID 501255Notes

Reaction equation

HRID 501255 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][S:11](=[O:14])(=[O:13])[N:10]([C:15]3[C:26]([S:27]([CH3:30])(=[O:29])=[O:28])=[CH:25][C:18]([C:19]([NH:21][C:22]([NH2:24])=[NH:23])=[O:20])=[C:17]([CH3:31])[CH:16]=3)[CH2:9]2)=[CH:4][CH:3]=1.[ClH:32]>>[ClH:32].[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][S:11](=[O:13])(=[O:14])[N:10]([C:15]3[C:26]([S:27]([CH3:30])(=[O:29])=[O:28])=[CH:25][C:18]([C:19]([NH:21][C:22]([NH2:24])=[NH:23])=[O:20])=[C:17]([CH3:31])[CH:16]=3)[CH2:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178427991HCID 178427991, compound

Product 1

HCID 178427992HCID 178427992, compound

Procedure

5.00 g of N-{4-[4-(4-fluorophenyl)-1,1-dioxoisothiazolidin-2-yl]-5-methanesulfonyl-2-methylbenzoyl}guanidine enantiomer B were converted into the hydrochloride in analogy to Example 7h), and 5.32 g of white crystals were obtained.

Workup

  1. customwere obtained

Sources & evidence

ORD record
ord-62908cafb6bf4196bb8072505e61f7ef
Source dataset
uspto-grants-2010_08
Patent number
US07772262B2

Reaction notes

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