HCID 59011488, compound → HCID 59011487, compound

HRID 501258Notes

Reaction equation

HRID 501258 reaction equation
[CH:1]1([N:4]2[S:8](=[O:10])(=[O:9])[N:7](C(OC(C)(C)C)=O)[CH2:6][CH2:5]2)[CH2:3][CH2:2]1>C(Cl)Cl.FC(F)(F)C(O)=O>[CH:1]1([N:4]2[CH2:5][CH2:6][NH:7][S:8]2(=[O:10])=[O:9])[CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 59011488HCID 59011488, compound

Product 1

HCID 59011487HCID 59011487, compoundYield 165.8%

Reagents, catalysts & solvents 1

HCID 21863450Trifluoroacetic acid methylene chlorideSolvent

Procedure

400 mg of tert-butyl 5-cyclopropyl-1,1-dioxo-[1,2,5]thiadiazolidine-2-carboxylate were dissolved in 10 ml of CH2Cl2/trifluoroacetic acid 1:1 and left to stand for 2 hours. The volatile constituents were removed in vacuo and coevaporated twice with 50 ml of CH2Cl2 each time. 410 mg of pale yellow oil were obtained and were directly employed further.

Workup

  1. waitleft
  2. customThe volatile constituents were removed in vacuo

Sources & evidence

ORD record
ord-ccd0119f03f94d1c94da0a52a7fff3b5
Source dataset
uspto-grants-2010_08
Patent number
US07772262B2

Reaction notes

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