HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 4-fluoro-3-(trifluoromethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Fluoro-3-(trifluoromethyl)benzoic acid | HCID 522268 | — |
| Product | Methyl 4-fluoro-3-(trifluoromethyl)benzoate | HCID 15285559 | — |
Reaction Steps
5 g of 4-fluoro-3-trifluoromethylbenzoic acid and 9 ml SOCl2 were stirred in 50 ml of MeOH at 60° C. for 8 h. The volatile constituents were then removed in vacuo to result in 5.1 g of a colorless oil, which was employed further without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772262B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-6d454815186d450a96a3bbd3bdc87d25 |
| Source note | uspto-grants-2010_08 |