HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)piperidine-1-carbonyl chloride → 6-Fluoro-1-(4-trifluoromethylpiperidine-1-carbonyl)-1H-indazol-3-yl 4-trifluoromethylpiperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)piperidine-1-carbonyl chloride | HCID 79887081 | — |
| Reactant | HCID 178518961 | HCID 178518961 | — |
| Product | 6-Fluoro-1-(4-trifluoromethylpiperidine-1-carbonyl)-1H-indazol-3-yl 4-trifluoromethylpiperidine-1-carboxylate | HCID 86624820 | — |
Reaction Steps
In analogy to example 1, 200 mg (1.315 mmol) of 6-fluoro-1H-indazol-3-ol were reacted with 340 mg (1.578 mmol) of 4-trifluoromethylpiperidine-1-carbonyl chloride. Yield: 8 mg (1%), M+H+: 511.36.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772268B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-83035950052b4f24a61b682402deb4ea |
| Source note | uspto-grants-2010_08 |