HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethylmorpholine-4-carbonyl chloride → 1-(2,6-Dimethylmorpholine-4-carbonyl)-6-fluoro-1H-indazol-3-yl 2,6-dimethylmorpholine-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethylmorpholine-4-carbonyl chloride | HCID 19080228 | — |
| Reactant | HCID 178518961 | HCID 178518961 | — |
| Product | 1-(2,6-Dimethylmorpholine-4-carbonyl)-6-fluoro-1H-indazol-3-yl 2,6-dimethylmorpholine-4-carboxylate | HCID 68455418 | — |
Reaction Steps
In analogy to example 1, 200 mg (1.315 mmol) of 6-fluoro-1H-indazol-3-ol were reacted with 280.3 mg (1.578 mmol) of 2,6-dimethylmorpholine-4-carbonyl chloride. Yield: 16 mg (3%), M+H+: 435.29.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772268B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-e8daa9859f814734875d0d044582f137 |
| Source note | uspto-grants-2010_08 |